Category Archives: New Research

Scaling Up Improved Inpatient Treatment of Severe Malnutrition: Key Factors and Experiences From South Africa, Bolivia, Malawi, and Ghana

EXCERPTS FROM THE PAPER Severe acute malnutrition (SAM) can have high mortality, especially in very ill children treated in the hospital. Many medical and nursing schools do not adequately, if at all, teach how to manage children with SAM. There is a dearth of experienced practitioners and trainers to serve as exemplars of good practice […]

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Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrhoeal disease in children in low-and-middle income countries: A systematic review and meta-analysis

The review found that WASH interventions reduced risk of diarrhoea in children in LMICs. Interventions supplying either water filtered at POU, higher water quality from an improved source on premises, or basic sanitation services with sewer connection were associated with increased reductions. Rear full paper.

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ICONIC: A GLOBAL VOICE ON NUTRITION AND CANCER

The International Union of Nutrition Sciences established a formal task force in 2018, The International Collaboration on Nutrition in relation to Cancer (ICONIC) in order to promote and facilitate collaboration between the scientific communities engaged in nutrition and cancer in research, education and training, and in clinical or public health practice. ICONIC is comprised of […]

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Effectiveness of Interventions for Managing Acute Malnutrition in Children under Five Years of Age in Low-Income and Middle-Income Countries: A Systematic Review and Meta-Analysis

Excerpts from the Abstract This review summarizes findings from a total of 42 studies (48 papers), including 35,017 children and reported some benefit of integrated community-based screening, identification, and management of SAM and MAM on improving recovery rate. The authors also found that facility-based screening and management of uncomplicated SAM has no effect on recovery […]

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Identifying SAM children: MUAC and/or Weight-for-Height

Grellety and Golden (2018) have published 3 new papers which challenge the use of MUAC solely for identification of children with Severe Acute Malnutrition. Access the full papers below: Severely malnourished children with a low weight-for-height have a higher mortality than those with a low mid-upper-arm-circumference: I. Empirical data demonstrates Simpson’s paradox link Severely malnourished […]

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Papers on nutritious complementary feeding to improve nutrition and prevent childhood undernutrition

These papers are part of Supplement of MCN on Policy, Program and Innovation in Complementary Feeding sponsored by Sight and Life. They are free access and provide evidence from research on nutritious complementary feeding for the prevention of childhood undernutrition. Links to the papers are available via Sight and Life website at Supplement for MCN […]

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Treatment of severe and moderate acute malnutrition in low- and middle-income settings: a systematic review, meta-analysis and Delphi process

This systematic review evaluates the effectiveness of interventions for SAM including the World Health Organization (WHO) protocol for inpatient management and community-based management with ready-to-use-therapeutic food (RUTF), as well as interventions for MAM in children under five years in low- and middle-income countries. Link

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Specially formulated foods for treating children with moderate acute malnutrition in low- and middle-income con tries (Review)

The study evaluated the safety and effectiveness of different types of specially formulated foods for children with moderate acute malnutrition in low- and middle-income countries, and to assess whether foods complying or not complying with specific nutritional compositions, such as the WHO technical specifications, are safe and effective. Download

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Effect of provision of daily zinc and iron with several micronutrients on growth and morbidity among young children in Pakistan: a cluster-randomised trial

A study among Pakistani children has found that the use of micronutrient powders reduces iron-deficiency. In this cluster-randomised trial, Soofi and colleagues concluded that the excess burden of diarrhoea and respiratory morbidities associated with micronutrient powder use and the very small effect on growth recorded suggest that a careful assessment of risks and benefits must […]

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Do Children with Uncomplicated Severe Acute Malnutrition Need Antibiotics? A Systematic Review and Meta-Analysis

A recent systematic review has concluded that the evidence underlying current antibiotic recommendations for uncomplicated SAM is weak. Susceptibility studies favour amoxicillin over cotrimoxazole. However, given that these antibiotics have side-effects, costs, and risks as well as benefits, their routine use needs urgent testing. With reliable monitoring, we believe that there is sufficient equipoise for […]

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